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Watch Itazura na Kiss online: Episode 22 The Best Gift

It is Kotoko's birthday and Irie takes her out for the night. Irie and Kotoko are very 'lovey dovey' in this episode. Irie and Kotoko pull an all-nighter at the hospital as a lot of emergencies came in, Kotoko stayed even though she seemed to have a fever. When Kotoko returns home in the morning, Oba-chan looks worried over her appearance and asks her if she's alright, Kotoko thinks she's running a slight fever, but Irie asks everyone to wait a moment, he asks Kotoko if she's pregnant, Oba-chan and Yuki both get a shock and yell 'what!'.The episode is left at a cliffhanger.

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