In the 21st Treehouse of Horror episode: Bart and Milhouse discover a real-life board game that they must win to return home in "War and Pieces"; Lisa falls in love with a moody, preteen vampire in the Twilight parody "Tweenlight"; and Marge and Homer go on a honeymoon on a sailboat, and rescue a castaway named Roger who tries to kill them in the Dead Calm parody "Master and Cadaver".
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Ready to Watch The Simpsons, Season 22, Episode 4?