Tenma is willing to take on Alone in combat as he injured Sisyphus seriously and freezed the Golden Saints. Pegasus, along with the Paope. try to seal Hades in the Great Tower, but they fail because of Pandora. She confronts Sasha about being born as Hades sister. Tenma, shocked, looks how Alone and Pandora flee, but he is not willing to let them escape. But despite his eforts Hades leaves, leaving the message that all will die when hi finishes his painting: The Lost Canvas, a painting that holds every human soul on earth.
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