The immortal mutant Apocalypse turns mutants who journeyed to Muir Island seeking the fictitious cure into the Horsemen Famine, Pestilence, War, and Death. The Horsemen start destroying everything across the planet. The X-Men arrive and battle the Horsemen. Rogue eventually grabs Archangel and absorbs his memory, sucking Apocalypse's power out of him. Archangel, appalled at what he has become, blasts the other Horsemen away. Apocalypse flees in a spaceship, and the diversion allows the other Horsemen to escape also.
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