This was the first cartoon to feature Wile E. Coyote and Road Runner. It set the template for the series, in which Wile E. Coyote (here given the ersatz Latin name Carnivorous Vulgaris) tries to catch Roadrunner (Accelleratti Incredibus) through many traps, plans and products, although in this first cartoon not all of the products are yet made by the Acme Corporation.
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Ready to Watch Looney Tunes, Season 1949, Episode 24?