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Watch Childrens Hospital ITV online: Episode 1 Children's Hospital at Christmas

20-month-old Harrison has relied on a breathing tube for the past seven months. He’s now facing major surgery to widen his windpipe. If it’s a success he’ll go into the new year with the hope of finally breathing on his own again. Brothers 9-year-old Archie and 7-year-old Isaac share a rare, hereditary form of dwarfism called Morquios which only affects 100 people in the UK. They are now coming to the end of a 72 week trial of a drug that could stop their disease from progressing.

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